Second Session：A Series of Lectures on International Frontiers
地點：圖書館群楼4樓報告廳 Location: 4th floor conference hall, Library
Shi, Yigong, professor, structural biologist. He received his bachelor's degree from Tsinghua University and PhD degree in Biophysics from Johns Hopkins University. He was the full professor and Warner-Lambert/Parke-Davis Professor in the department of Molecular Biology at Princeton University. In 2008, he came back and pursued his career at Tsinghua University, becoming the dean of the School of Life Sciences there and later in 2015 appointed the vice-president of Tsinghua university. In 2013, Shi was elected as academician of the American Academy of Arts and Sciences, foreign academician of the American Academy of Sciences, academician of Chinese Academy of Sciences, respectively. In 2018, Shi left Tsinghua university and dedicated himself to the establishment of Xihu University, being the first president of it.
Shi studied the molecular mechanisms that govern the awakening of apoptotic enzymes in worms, fruit flies, and mammals, seeking to illuminate function by revealing their structures. He and his laboratory have solved the structures of more than 40 proteins and protein complexes. To date Shi has published more than one hundred of papers on international academic journals, including 18 on Cell, 24 on Nature, 15 on Science, which elucidated the structure and interaction mechanism of proteins involved in cell apoptosis pathway. Many of his achievements have been protected by patents, used for the research and development of drugs in the treatment of cancers.